| [Member (365WT)]answers [Chinese ] | Time :2018-11-22 | Diazotization refers to the reaction of a primary amine with nitrous acid at a low temperature to form a diazonium salt. The reaction of aromatic primary amine and nitrous acid to form diazonium salt is marked as diazotization, aryl primary amine is often called diazo component, and nitrous acid is diazotizing agent. Because nitrous acid is unstable, sodium nitrite and hydrochloric acid are usually used. Or sulfuric acid, the nitrous acid formed during the reaction is immediately reacted with the aromatic primary amine to avoid the decomposition of nitrous acid, and the diazonium salt is formed after the diazotization reaction. Aliphatic, aromatic and heterocyclic primary amines can be subjected to diazotization.
Acid dosage
2mol
temperature reflex
0-5 ° C |
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